Interesting. I was considering doing magic mushrooms precisely with that goal. Can you please elaborate? What did you think/feel about while high, and how did it rewire you? Is there a connection you can see in retrospect?

It is a known personality issue.

It is called avoidant personality disorder (AVPD) or schizoid personality disorder (SPD). Both of these conditions can lead to feelings of loneliness due to inner walls and barriers that the person builds to protect themselves from perceived threats or emotional pain.